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GENERAL
TITLE
CRYSTAL STRUCTURE OF THE ACVR1 (ALK2) KINASE IN COMPLEX WITH THE COMPOUND SARACATINIB (AZD0530)
DATE LAST MODIFIED
26 May 2021
RELEASE
29 Jul 2020
OBSOLETE
CLASSIFICATION
SIGNALING PROTEIN
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
I 1 2 1
RESOLUTION RANGE HIGH
2.66
RESOLUTION RANGE LOW
44.84
PUBMED ID
DOI
10.1172/JCI.INSIGHT.95042

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
Q04771 ACVR1 SPODOPTERA FRUGIPERDA HUMAN -- Mutations
Q04771 ACVR1 SPODOPTERA FRUGIPERDA HUMAN -- Mutations
Q04771 ACVR1 SPODOPTERA FRUGIPERDA HUMAN -- Mutations
Q04771 ACVR1 SPODOPTERA FRUGIPERDA HUMAN -- Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402