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GENERAL
TITLE
[1,2,4]TRIAZOLO[1,5-A]PYRIMIDINE PHOSPHODIESTERASE 2 INHIBITORS
DATE LAST MODIFIED
25 Nov 2020
RELEASE
22 Jul 2020
OBSOLETE
CLASSIFICATION
HYDROLASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 1 2 1
RESOLUTION RANGE HIGH
2.35
RESOLUTION RANGE LOW
85.51
PUBMED ID
DOI
10.1021/ACS.JMEDCHEM.0C01272
PDBe
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Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
O00408 PDE2A SPODOPTERA FRUGIPERDA HUMAN CYCLIC GMP-STIMULATED PHOSPHODIESTERASE,CGSPDE HUMAN
CYCLIC GMP-STIMULATED PHOSPHODIESTERASE,CGSPDE
Mutations
O00408 PDE2A SPODOPTERA FRUGIPERDA HUMAN CYCLIC GMP-STIMULATED PHOSPHODIESTERASE,CGSPDE HUMAN
CYCLIC GMP-STIMULATED PHOSPHODIESTERASE,CGSPDE
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402