6ZQZ

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 6ZQZ_1

Bioassembly 6ZQZ_2

Chain 6ZQZ_A

Chain 6ZQZ_B

Chain 6ZQZ_C

Chain 6ZQZ_D

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GENERAL

TITLE

[1,2,4]TRIAZOLO[1,5-A]PYRIMIDINE PHOSPHODIESTERASE 2 INHIBITORS

DATE LAST MODIFIED

25 Nov 2020

RELEASE

4 Nov 2020

OBSOLETE

CLASSIFICATION

HYDROLASE

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 1

RESOLUTION RANGE HIGH

1.88

RESOLUTION RANGE LOW

87.07

PUBMED ID

DOI

10.1021/ACS.JMEDCHEM.0C01272

PDBe

LIGANDS

Target Protein	Gene	Expression System	Organism	Synonyms	Actions
O00408	PDE2A	SPODOPTERA FRUGIPERDA	HUMAN	CYCLIC GMP-STIMULATED PHOSPHODIESTERASE,CGSPDE	HUMAN	CYCLIC GMP-STIMULATED PHOSPHODIESTERASE,CGSPDE	Mutations
O00408	PDE2A	SPODOPTERA FRUGIPERDA	HUMAN	CYCLIC GMP-STIMULATED PHOSPHODIESTERASE,CGSPDE	HUMAN	CYCLIC GMP-STIMULATED PHOSPHODIESTERASE,CGSPDE	Mutations
O00408	PDE2A	SPODOPTERA FRUGIPERDA	HUMAN	CYCLIC GMP-STIMULATED PHOSPHODIESTERASE,CGSPDE	HUMAN	CYCLIC GMP-STIMULATED PHOSPHODIESTERASE,CGSPDE	Mutations
O00408	PDE2A	SPODOPTERA FRUGIPERDA	HUMAN	CYCLIC GMP-STIMULATED PHOSPHODIESTERASE,CGSPDE	HUMAN	CYCLIC GMP-STIMULATED PHOSPHODIESTERASE,CGSPDE	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402