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GENERAL
TITLE
CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN PARP1 IN COMPLEX WITH VELIPARIB
DATE LAST MODIFIED
10 Mar 2021
RELEASE
13 Jan 2021
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
1.59
RESOLUTION RANGE LOW
81.015
PUBMED ID
DOI
10.1093/NAR/GKAB020

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P09874 PARP1, ADPRT, PPOL ESCHERICHIA COLI BL21(DE3) HUMAN PARP-1,ADP-RIBOSYLTRANSFERASE DIPHTHERIA TOXIN-LIKE 1,ARTD1,DNA ADP-RIBOSYLTRANSFERASE PARP1,NAD(+) ADP-RIBOSYLTRANSFERASE 1,ADPRT 1,POLY[ADP-RIBOSE] SYNTHASE 1,PROTEIN POLY-ADP-RIBOSYLTRANSFERASE PARP1 HUMAN
PARP-1,ADP-RIBOSYLTRANSFERASE DIPHTHERIA TOXIN-LIK ...
Mutations
P09874 PARP1, ADPRT, PPOL ESCHERICHIA COLI BL21(DE3) HUMAN PARP-1,ADP-RIBOSYLTRANSFERASE DIPHTHERIA TOXIN-LIKE 1,ARTD1,DNA ADP-RIBOSYLTRANSFERASE PARP1,NAD(+) ADP-RIBOSYLTRANSFERASE 1,ADPRT 1,POLY[ADP-RIBOSE] SYNTHASE 1,PROTEIN POLY-ADP-RIBOSYLTRANSFERASE PARP1 HUMAN
PARP-1,ADP-RIBOSYLTRANSFERASE DIPHTHERIA TOXIN-LIK ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402