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GENERAL
TITLE
CRYO-EM STRUCTURE OF HUMAN ER MEMBRANE PROTEIN COMPLEX IN LIPID NANODISCS
DATE LAST MODIFIED
20 Jan 2021
RELEASE
2 Dec 2020
OBSOLETE
CLASSIFICATION
MEMBRANE PROTEIN
EXPERIMENT TYPE
ELECTRON MICROSCOPY
SPACE GROUP
P 1
RESOLUTION RANGE HIGH
3.39
RESOLUTION RANGE LOW
3.39
PUBMED ID
DOI
10.7554/ELIFE.62611
PDBe
--

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
Q8N766 EMC1, KIAA0090, PSEC0263 HOMO SAPIENS HUMAN -- HUMAN -- Mutations
Q15006 EMC2, KIAA0103, TTC35 HOMO SAPIENS HUMAN TETRATRICOPEPTIDE REPEAT PROTEIN 35,TPR REPEAT PROTEIN 35 HUMAN
TETRATRICOPEPTIDE REPEAT PROTEIN 35,TPR REPEAT PRO ...
Mutations
Q9P0I2 EMC3, TMEM111 HOMO SAPIENS HUMAN TRANSMEMBRANE PROTEIN 111 HUMAN
TRANSMEMBRANE PROTEIN 111
Mutations
Q5J8M3 EMC4, TMEM85, HSPC184, PIG17 HOMO SAPIENS HUMAN CELL PROLIFERATION-INDUCING GENE 17 PROTEIN,TRANSMEMBRANEPROTEIN 85INPUT ARE NOT ALIGNING WELL. HUMAN
CELL PROLIFERATION-INDUCING GENE 17 PROTEIN,TRANSM ...
Mutations
Q8N4V1 MMGT1, EMC5, TMEM32 HOMO SAPIENS HUMAN ER MEMBRANE PROTEIN COMPLEX SUBUNIT 5,TRANSMEMBRANE PROTEIN32 HUMAN
ER MEMBRANE PROTEIN COMPLEX SUBUNIT 5,TRANSMEMBRAN ...
Mutations
Q9BV81 EMC6, TMEM93 HOMO SAPIENS HUMAN TRANSMEMBRANE PROTEIN 93 HUMAN
TRANSMEMBRANE PROTEIN 93
Mutations
Q9NPA0 EMC7, C11ORF3, C15ORF24, HT022, UNQ905/PRO1926 HOMO SAPIENS HUMAN -- HUMAN -- Mutations
O43402 EMC8, C16ORF2, C16ORF4, COX4AL, COX4NB, FAM158B, NOC4 HOMO SAPIENS HUMAN NEIGHBOR OF COX4,PROTEIN FAM158B(44% IDENTITY) WERE CO-EXPRESSED AND TURNS OUT THEY CAN BOTH OCCUPYSAME POSITION ON COMPLEX IN MUTUALLY EXCLUSIVE MANNER. WE CHOSE TOMODEL AS EMC8 BUT NOTE THAT MAP IS LIKELY SUPERPOSITION OF BOTH. HUMAN
NEIGHBOR OF COX4,PROTEIN FAM158B(44% IDENTITY) WER ...
Mutations
Q5UCC4 EMC10, C19ORF63, HSM1, INM02, UNQ764/PRO1556 HOMO SAPIENS HUMAN HEMATOPOIETIC SIGNAL PEPTIDE-CONTAINING MEMBRANE DOMAIN-CONTAINING PROTEIN 1 HUMAN
HEMATOPOIETIC SIGNAL PEPTIDE-CONTAINING MEMBRANE D ...
Mutations
-- HOMO SAPIENS HOMO SAPIENS -- HOMO SAPIENS --
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402