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GENERAL
TITLE
CRYSTAL STRUCTURE OF NLRP3 NACHT DOMAIN IN COMPLEX WITH A POTENT INHIBITOR
DATE LAST MODIFIED
17 Nov 2021
RELEASE
20 Oct 2021
OBSOLETE
CLASSIFICATION
IMMUNE SYSTEM
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 61 2 2
RESOLUTION RANGE HIGH
2.83
RESOLUTION RANGE LOW
79.394
PUBMED ID
DOI
10.1016/J.JMB.2021.167309
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
Q96P20 NLRP3, C1ORF7, CIAS1, NALP3, PYPAF1 UNIDENTIFIED BACULOVIRUS HUMAN ANGIOTENSIN/VASOPRESSIN RECEPTOR AII/AVP-LIKE,CATERPILLERPROTEIN 1.1,CLR1.1,COLD-INDUCED AUTOINFLAMMATORY SYNDROME 1 PROTEIN,CRYOPYRIN,PYRIN-CONTAINING APAF1-LIKE PROTEIN 1 HUMAN
ANGIOTENSIN/VASOPRESSIN RECEPTOR AII/AVP-LIKE,CATE ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402