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GENERAL
TITLE
STRUCTURE OF NUDT15 IN COMPLEX WITH GANCICLOVIR TRIPHOSPHATE
DATE LAST MODIFIED
29 Dec 2021
RELEASE
2 Jun 2021
OBSOLETE
CLASSIFICATION
HYDROLASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
1.95
RESOLUTION RANGE LOW
46.5
PUBMED ID
DOI
10.1016/J.CHEMBIOL.2021.06.001
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
Q9NV35 NUDT15, MTH2 ESCHERICHIA COLI BL21(DE3) HUMAN 8-OXO-DGTPASE NUDT15,7,8-DIHYDRO-8-OXOGUANINE-TRIPHOSPHATASENUDT15,MUTT HOMOLOG 2,MTH2,NUCLEOSIDE DIPHOSPHATE-LINKED MOIETY XMOTIF 15,NUDIX MOTIF 15 HUMAN
8-OXO-DGTPASE NUDT15,7,8-DIHYDRO-8-OXOGUANINE-TRIP ...
Mutations
Q9NV35 NUDT15, MTH2 ESCHERICHIA COLI BL21(DE3) HUMAN 8-OXO-DGTPASE NUDT15,7,8-DIHYDRO-8-OXOGUANINE-TRIPHOSPHATASENUDT15,MUTT HOMOLOG 2,MTH2,NUCLEOSIDE DIPHOSPHATE-LINKED MOIETY XMOTIF 15,NUDIX MOTIF 15 HUMAN
8-OXO-DGTPASE NUDT15,7,8-DIHYDRO-8-OXOGUANINE-TRIP ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402