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GENERAL
TITLE
STRUCTURE OF THE THERMOSTABILIZED EAAT1 CRYST-E386Q MUTANT IN COMPLEX WITH L-ASP, SODIUM IONS AND THE ALLOSTERIC INHIBITOR UCPH101
DATE LAST MODIFIED
19 Jan 2022
RELEASE
13 Oct 2021
OBSOLETE
CLASSIFICATION
MEMBRANE PROTEIN
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 63
RESOLUTION RANGE HIGH
3.65
RESOLUTION RANGE LOW
28
PUBMED ID
DOI
10.15252/EMBJ.2021108341

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
Q15758 SLC1A3, EAAT1, GLAST, GLAST1, SLC1A5, ASCT2, M7V1, RDR, RDRC HOMO SAPIENS HUMAN SODIUM-DEPENDENT GLUTAMATE/ASPARTATE TRANSPORTER 1,GLAST-1,SOLUTE CARRIER FAMILY 1 MEMBER 3,ATB(0),BABOON M7 VIRUS RECEPTOR,RD114/SIMIAN TYPE D RETROVIRUS RECEPTOR,SODIUM-DEPENDENT NEUTRALAMINO ACID TRANSPORTER TYPE 2,SOLUTE CARRIER FAMILY 1 MEMBER 5,SODIUM-DEPENDENT GLUTAMATE/ASPARTATE TRANSPORTER 1,GLAST-1,SOLUTECARRIER FAMILY 1 MEMBER 3BOUND,L-ASP, SODIUM IONS AND ALLOSTERIC INHIBITOR UCPH101 BOUND,L-ASP, SODIUM IONS AND ALLOSTERIC INHIBITOR UCPH101 BOUND,L-ASP, SODIUMIONS AND ALLOSTERIC INHIBITOR UCPH101 BOUND,L-ASP, SODIUM IONS ANDALLOSTERIC INHIBITOR UCPH101 BOUND,L-ASP, SODIUM IONS AND ALLOSTERICINHIBITOR UCPH101 BOUND,L-ASP, SODIUM IONS AND ALLOSTERIC INHIBITORUCPH101 BOUND,L-ASP, SODIUM IONS AND ALLOSTERIC INHIBITOR UCPH101BOUND,L-ASP, SODIUM IONS AND ALLOSTERIC INHIBITOR UCPH101 BOUND HUMAN
SODIUM-DEPENDENT GLUTAMATE/ASPARTATE TRANSPORTER 1 ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402