7B4F

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 7B4F_1

Chain 7B4F_A

Chain 7B4F_B

Spin

Focus

Transparency

More Info

GENERAL

TITLE

STRUCTURAL BASIS OF REACTIVATION OF ONCOGENIC P53 MUTANTS BY A SMALL MOLECULE: METHYLENE QUINUCLIDINONE (MQ). HUMAN P53DBD-R282W MUTANT BOUND TO DNA: R282W-MQ (I)

DATE LAST MODIFIED

15 Dec 2021

RELEASE

8 Dec 2021

OBSOLETE

CLASSIFICATION

TRANSCRIPTION

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

C 1 2 1

RESOLUTION RANGE HIGH

1.78

RESOLUTION RANGE LOW

PUBMED ID

34862374

DOI

10.1038/S41467-021-27142-6

PDBe

LIGANDS

, 23

Chains

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P04584	TP53, P53	ESCHERICHIA COLI BL21(DE3)	HUMAN	ANTIGEN NY-CO-13,PHOSPHOPROTEIN P53,TUMOR SUPPRESS ...
	P04584	--	--	SYNTHETIC CONSTRUCT	--

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402