7BJ0 logo

7BJ0

3D Structure View

Loading...

More Info

GENERAL
TITLE
INHIBITOR OF MDM2-P53 INTERACTION
DATE LAST MODIFIED
21 Apr 2021
RELEASE
7 Apr 2021
OBSOLETE
CLASSIFICATION
APOPTOSIS
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 31 2 1
RESOLUTION RANGE HIGH
2
RESOLUTION RANGE LOW
83.6
PUBMED ID
DOI
10.1021/ACS.JMEDCHEM.0C02188
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
Q00987 MDM2 ESCHERICHIA COLI BL21(DE3) HUMAN DOUBLE MINUTE 2 PROTEIN,HDM2,ONCOPROTEIN MDM2,RING-TYPE E3UBIQUITIN TRANSFERASE MDM2,P53-BINDING PROTEIN MDM2 HUMAN
DOUBLE MINUTE 2 PROTEIN,HDM2,ONCOPROTEIN MDM2,RING ...
Mutations
Q00987 MDM2 ESCHERICHIA COLI BL21(DE3) HUMAN DOUBLE MINUTE 2 PROTEIN,HDM2,ONCOPROTEIN MDM2,RING-TYPE E3UBIQUITIN TRANSFERASE MDM2,P53-BINDING PROTEIN MDM2 HUMAN
DOUBLE MINUTE 2 PROTEIN,HDM2,ONCOPROTEIN MDM2,RING ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402