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GENERAL
TITLE
ATP-COMPETITIVE PARTIAL ANTAGONISTS-'PAIR'S-RHEOSTATICALLY MODULATE IRE1ALPHA'S KINASE HELIX-ALPHAC TO SEGREGATE ITS RNASE-MEDIATED BIOLOGICAL OUTPUTS
DATE LAST MODIFIED
13 Apr 2022
RELEASE
29 Sept 2021
OBSOLETE
CLASSIFICATION
UNKNOWN FUNCTION
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 1 2 1
RESOLUTION RANGE HIGH
1.85
RESOLUTION RANGE LOW
91.59
PUBMED ID
DOI
10.1038/S41589-021-00852-0
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
O75460 ERN1, IRE1 SPODOPTERA FRUGIPERDA HUMAN ENDOPLASMIC RETICULUM-TO-NUCLEUS SIGNALING 1,INOSITOL-REQUIRING PROTEIN 1,HIRE1P,IRE1-ALPHA,IRE1A HUMAN
ENDOPLASMIC RETICULUM-TO-NUCLEUS SIGNALING 1,INOSI ...
Mutations
O75460 ERN1, IRE1 SPODOPTERA FRUGIPERDA HUMAN ENDOPLASMIC RETICULUM-TO-NUCLEUS SIGNALING 1,INOSITOL-REQUIRING PROTEIN 1,HIRE1P,IRE1-ALPHA,IRE1A HUMAN
ENDOPLASMIC RETICULUM-TO-NUCLEUS SIGNALING 1,INOSI ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402