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GENERAL
TITLE
CRYSTAL STRUCTURE OF EHMT2 SET DOMAIN IN COMPLEX WITH COMPOUND 13
DATE LAST MODIFIED
16 Jun 2021
RELEASE
11 Nov 2020
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
2.6
RESOLUTION RANGE LOW
78.43
PUBMED ID
DOI
10.1016/J.BMCL.2020.127475
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
Q96KQ7 EHMT2, BAT8, C6ORF30, G9A, KMT1C, NG36 ESCHERICHIA COLI BL21(DE3) HUMAN EUCHROMATIC HISTONE-LYSINE N-METHYLTRANSFERASE 2,HLA-B-ASSOCIATED TRANSCRIPT 8,HISTONE H3-K9 METHYLTRANSFERASE 3,H3-K9-HMTASE 3,LYSINE N-METHYLTRANSFERASE 1C,PROTEIN G9A HUMAN
EUCHROMATIC HISTONE-LYSINE N-METHYLTRANSFERASE 2,H ...
Mutations
Q96KQ7 EHMT2, BAT8, C6ORF30, G9A, KMT1C, NG36 ESCHERICHIA COLI BL21(DE3) HUMAN EUCHROMATIC HISTONE-LYSINE N-METHYLTRANSFERASE 2,HLA-B-ASSOCIATED TRANSCRIPT 8,HISTONE H3-K9 METHYLTRANSFERASE 3,H3-K9-HMTASE 3,LYSINE N-METHYLTRANSFERASE 1C,PROTEIN G9A HUMAN
EUCHROMATIC HISTONE-LYSINE N-METHYLTRANSFERASE 2,H ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402