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GENERAL
TITLE
CRYSTAL STRUCTURE OF BACE1 IN COMPLEX WITH N-{3-[(4R,5R,6R)-2-AMINO-5- FLUORO-4,6-DIMETHYL-5,6-DIHYDRO-4H-1,3-THIAZIN-4-YL]-4-FLUOROPHENYL}- 2H,3H-[1,4]DIOXINO[2,3-C]PYRIDINE-7-CARBOXAMIDE
DATE LAST MODIFIED
-
RELEASE
23 Feb 2022
OBSOLETE
CLASSIFICATION
HYDROLASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 61 2 2
RESOLUTION RANGE HIGH
2.05
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1021/ACS.JMEDCHEM.1C00359
PDBe
--
LIGANDS
--
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonims | Actions |
|---|---|---|---|---|---|---|
| P36776 | BACE1, BACE, KIAA1149 | ESCHERICHIA COLI | HUMAN | ASPARTYL PROTEASE 2,ASP 2,BETA-SITE AMYLOID PRECUR ... |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402