3D Structure View
Loading...
More Info
GENERAL
TITLE
EGFR KINASE (T790M/V948R) IN COMPLEX WITH OSIMERTINIB AND JBJ-09-063
DATE LAST MODIFIED
18 May 2022
RELEASE
8 Sept 2021
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 1 2 1
RESOLUTION RANGE HIGH
2.5
RESOLUTION RANGE LOW
65.64
PUBMED ID
-
DOI
10.1038/S41467-022-30258-Y
PDBe
7JXW
LIGANDS
,
728282
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonims | Actions |
|---|---|---|---|---|---|---|
| P00533 | EGFR, ERBB, ERBB1, HER1 | SPODOPTERA FRUGIPERDA | HUMAN | PROTO-ONCOGENE C-ERBB-1,RECEPTOR TYROSINE-PROTEIN ... | Mutations | |
| Q8V4T7 | EGFR, ERBB, ERBB1, HER1 | SPODOPTERA FRUGIPERDA | HUMAN | PROTO-ONCOGENE C-ERBB-1,RECEPTOR TYROSINE-PROTEIN ... | ||
| P28574 | EGFR, ERBB, ERBB1, HER1 | SPODOPTERA FRUGIPERDA | HUMAN | PROTO-ONCOGENE C-ERBB-1,RECEPTOR TYROSINE-PROTEIN ... | ||
| P01106 | EGFR, ERBB, ERBB1, HER1 | SPODOPTERA FRUGIPERDA | HUMAN | PROTO-ONCOGENE C-ERBB-1,RECEPTOR TYROSINE-PROTEIN ... |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402