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GENERAL
TITLE
CRYSTAL STRUCTURE OF PLASMODIUM FALCIPARUM DIHYDROOROTATE DEHYDROGENASE BOUND WITH INHIBITOR DSM634 (3-METHYL-N-(1-(5- METHYLISOXAZOL-3-YL)ETHYL)-4-(4-(TRIFLUOROMETHYL)BENZYL)-1H-PYRROLE- 2-CARBOXAMIDE)
DATE LAST MODIFIED
8 Dec 2021
RELEASE
19 May 2021
OBSOLETE
CLASSIFICATION
OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 64
RESOLUTION RANGE HIGH
2.4
RESOLUTION RANGE LOW
42.64
PUBMED ID
DOI
10.1021/ACS.JMEDCHEM.1C00173
PDBe
Chains
Structure Chain | Target Protein | Gene | Expression System | Organism | Synonims | Actions |
---|---|---|---|---|---|---|
Q8TCJ2 | PFF0160C | ESCHERICHIA COLI | PLASMODIUM FALCIPARUM (ISOLATE 3D7) | DHODEHASE,DIHYDROOROTATE OXIDASE |