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GENERAL
TITLE
CRYO-EM STRUCTURE OF HSP90:FKBP51:P23 CLOSED-STATE COMPLEX
DATE LAST MODIFIED
15 Sept 2021
RELEASE
25 Aug 2021
OBSOLETE
CLASSIFICATION
ISOMERASE/CHAPERONE
EXPERIMENT TYPE
ELECTRON MICROSCOPY
SPACE GROUP
P 1
RESOLUTION RANGE HIGH
3.3
RESOLUTION RANGE LOW
3.3
PUBMED ID
DOI
10.1016/J.MOLCEL.2021.07.023
PDBe
--
LIGANDS
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonyms | Actions | ||
|---|---|---|---|---|---|---|---|---|
| P07900 | HSP90AA1, HSP90A, HSPC1, HSPCA | ESCHERICHIA COLI | HUMAN | HEAT SHOCK 86 KDA,HSP86,LIPOPOLYSACCHARIDE-ASSOCIATEDPROTEIN 2,LPS-ASSOCIATED PROTEIN 2,RENAL CARCINOMA ANTIGEN NY-REN-38 | HUMAN | HEAT SHOCK 86 KDA,HSP86,LIPOPOLYSACCHARIDE-ASSOCIA ... | Mutations | |
| P07900 | HSP90AA1, HSP90A, HSPC1, HSPCA | ESCHERICHIA COLI | HUMAN | HEAT SHOCK 86 KDA,HSP86,LIPOPOLYSACCHARIDE-ASSOCIATEDPROTEIN 2,LPS-ASSOCIATED PROTEIN 2,RENAL CARCINOMA ANTIGEN NY-REN-38 | HUMAN | HEAT SHOCK 86 KDA,HSP86,LIPOPOLYSACCHARIDE-ASSOCIA ... | Mutations | |
| Q13451 | FKBP5, AIG6, FKBP51 | ESCHERICHIA COLI | HUMAN | PPIASE FKBP5,51 KDA FK506-BINDING PROTEIN,FKBP-51,54 KDAPROGESTERONE RECEPTOR-ASSOCIATED IMMUNOPHILIN,ANDROGEN-REGULATEDPROTEIN 6,FF1 ANTIGEN,FK506-BINDING PROTEIN 5,FKBP-5,FKBP54,P54,HSP90-BINDING IMMUNOPHILIN,ROTAMASE | HUMAN | PPIASE FKBP5,51 KDA FK506-BINDING PROTEIN,FKBP-51, ... | Mutations | |
| Q15185 | PTGES3, P23, TEBP | ESCHERICHIA COLI | HUMAN | CYTOSOLIC PROSTAGLANDIN E2 SYNTHASE,CPGES,HSP90 CO-CHAPERONE,PROGESTERONE RECEPTOR COMPLEX P23,TELOMERASE-BINDINGPROTEIN P23 | HUMAN | CYTOSOLIC PROSTAGLANDIN E2 SYNTHASE,CPGES,HSP90 CO ... | Mutations |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402