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GENERAL
TITLE
CRYO-EM STRUCTURE OF P110ALPHA IN COMPLEX WITH P85ALPHA INHIBITED BY BYL-719
DATE LAST MODIFIED
24 Nov 2021
RELEASE
10 Nov 2021
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
ELECTRON MICROSCOPY
SPACE GROUP
P 1
RESOLUTION RANGE HIGH
2.92
RESOLUTION RANGE LOW
2.92
PUBMED ID
DOI
10.1073/PNAS.2109327118
PDBe
--
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P93025 PIK3CA TRICHOPLUSIA NI HUMAN
PTDINS-3-KINASE SUBUNIT ALPHA, PHOSPHATIDYLINOSITO ...
Q14511 PIK3R1, GRB1 TRICHOPLUSIA NI HUMAN
PI3-KINASE REGULATORY SUBUNIT ALPHA,PI3K REGULATOR ...
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402