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GENERAL
TITLE
CRYO-EM STRUCTURE OF HUMAN FULL-LENGTH BETA3DELTA GABA(A)R IN COMPLEX WITH HISTAMINE AND NANOBODY NB25
DATE LAST MODIFIED
20 Apr 2022
RELEASE
13 Apr 2022
OBSOLETE
CLASSIFICATION
MEMBRANE PROTEIN
EXPERIMENT TYPE
ELECTRON MICROSCOPY
SPACE GROUP
P 1
RESOLUTION RANGE HIGH
3.1
RESOLUTION RANGE LOW
3.1
PUBMED ID
DOI
10.1038/S41586-022-04517-3
PDBe
--
LIGANDS
--

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P23946 GABRB3 HOMO SAPIENS HUMAN
GABA(A) RECEPTOR SUBUNIT BETA-3
P28472 GABRB3 HOMO SAPIENS HUMAN
GABA(A) RECEPTOR SUBUNIT BETA-3
Mutations
Q8TAC2 GABRB3 HOMO SAPIENS HUMAN
GABA(A) RECEPTOR SUBUNIT BETA-3
P0CG47 GABRB3 HOMO SAPIENS HUMAN
GABA(A) RECEPTOR SUBUNIT BETA-3
P04951 GABRD HOMO SAPIENS HUMAN
GABA(A) RECEPTOR SUBUNIT DELTA
P01624 -- HOMO SAPIENS HOMO SAPIENS --
P04951 -- HOMO SAPIENS HOMO SAPIENS --
P07720 -- HOMO SAPIENS HOMO SAPIENS --
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402