3D Structure View
Loading...
More Info
GENERAL
TITLE
CRYO-EM STRUCTURE OF HUMAN FULL-LENGTH EXTRASYNAPTIC ALPHA4BETA3DELTA GABA(A)R IN COMPLEX WITH GABA, HISTAMINE AND NANOBODY NB25 IN A PRE- OPEN/CLOSED STATE
DATE LAST MODIFIED
20 Apr 2022
RELEASE
13 Apr 2022
OBSOLETE
CLASSIFICATION
MEMBRANE PROTEIN
EXPERIMENT TYPE
ELECTRON MICROSCOPY
SPACE GROUP
P 1
RESOLUTION RANGE HIGH
2.9
RESOLUTION RANGE LOW
2.9
PUBMED ID
DOI
10.1038/S41586-022-04517-3
PDBe
--
LIGANDS
--
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonims | Actions |
|---|---|---|---|---|---|---|
| P48169 | GABRA4 | HOMO SAPIENS | HUMAN | GABA(A) RECEPTOR SUBUNIT ALPHA-4 | Mutations | |
| P28472 | GABRB3 | HOMO SAPIENS | HUMAN | GABA(A) RECEPTOR SUBUNIT BETA-3 | Mutations | |
| P28472 | GABRB3 | HOMO SAPIENS | HUMAN | GABA(A) RECEPTOR SUBUNIT BETA-3 | Mutations | |
| P28472 | GABRB3 | HOMO SAPIENS | HUMAN | GABA(A) RECEPTOR SUBUNIT BETA-3 | Mutations | |
| O14764 | GABRD | HOMO SAPIENS | HUMAN | GABA(A) RECEPTOR SUBUNIT DELTA | Mutations | |
| -- | HOMO SAPIENS | HOMO SAPIENS | -- | |||
| -- | HOMO SAPIENS | HOMO SAPIENS | -- |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402