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GENERAL
TITLE
CRYO-EM STRUCTURE OF HUMAN ACKR3 IN COMPLEX WITH CXCL12, A SMALL MOLECULE PARTIAL AGONIST CCX662, AND AN EXTRACELLULAR FAB
DATE LAST MODIFIED
-
RELEASE
27 Jul 2022
OBSOLETE
CLASSIFICATION
SIGNALING PROTEIN/IMMUNE SYSTEM
EXPERIMENT TYPE
ELECTRON MICROSCOPY
SPACE GROUP
P 1
RESOLUTION RANGE HIGH
3.3
RESOLUTION RANGE LOW
3.3
PUBMED ID
DOI
10.1126/SCIADV.ABN8063
PDBe
--
LIGANDS
--
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonims | Actions |
|---|---|---|---|---|---|---|
| P25106 | ACKR3, CMKOR1, CXCR7, GPR159, RDC1 | SPODOPTERA FRUGIPERDA | HUMAN | C-X-C CHEMOKINE RECEPTOR TYPE 7,CXC-R7,CXCR-7,CHEM ... | Mutations | |
| P48061 | CXCL12, SDF1, SDF1A, SDF1B | ESCHERICHIA COLI 'BL21-GOLD(DE3)PLYSS AG' | HUMAN | HSDF-1,C-X-C MOTIF CHEMOKINE 12,INTERCRINE REDUCED ... | Mutations | |
| Q04771 | -- | ESCHERICHIA COLI 'BL21-GOLD(DE3)PLYSS AG' | HOMO SAPIENS | -- | ||
| -- | ESCHERICHIA COLI 'BL21-GOLD(DE3)PLYSS AG' | HOMO SAPIENS | -- | |||
| -- | ESCHERICHIA COLI | LAMA GLAMA | -- |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402