7TA6

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 7TA6_1

Chain 7TA6_A

Chain 7TA6_B

Chain 7TA6_C

Chain 7TA6_D

Chain 7TA6_E

Chain 7TA6_F

Chain 7TA6_G

Chain 7TA6_H

Chain 7TA6_I

Chain 7TA6_J

Chain 7TA6_K

Chain 7TA6_L

Chain 7TA6_M

Chain 7TA6_N

Chain 7TA6_O

Chain 7TA6_P

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GENERAL

TITLE

TRIMER-TO-MONOMER DISRUPTION OF TUMOR NECROSIS FACTOR-ALPHA (TNF- ALPHA) BY UNNATURAL ALPHA/BETA-PEPTIDE-1

DATE LAST MODIFIED

RELEASE

29 Jun 2022

OBSOLETE

CLASSIFICATION

SIGNALING PROTEIN

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

C 1 2 1

RESOLUTION RANGE HIGH

2.67

RESOLUTION RANGE LOW

101.11

PUBMED ID

35613436

DOI

10.1021/JACS.1C13717

PDBe

7TA6

LIGANDS

Chains

Target Protein	Gene	Expression System	Organism	Synonims	Actions
P01375	TNF, TNFA, TNFSF2	ESCHERICHIA COLI	HUMAN	CACHECTIN,TNF-ALPHA,TUMOR NECROSIS FACTOR LIGAND S ...	Mutations
P01375	TNF, TNFA, TNFSF2	ESCHERICHIA COLI	HUMAN	CACHECTIN,TNF-ALPHA,TUMOR NECROSIS FACTOR LIGAND S ...	Mutations
P01375	TNF, TNFA, TNFSF2	ESCHERICHIA COLI	HUMAN	CACHECTIN,TNF-ALPHA,TUMOR NECROSIS FACTOR LIGAND S ...	Mutations
P01375	TNF, TNFA, TNFSF2	ESCHERICHIA COLI	HUMAN	CACHECTIN,TNF-ALPHA,TUMOR NECROSIS FACTOR LIGAND S ...	Mutations
P01375	TNF, TNFA, TNFSF2	ESCHERICHIA COLI	HUMAN	CACHECTIN,TNF-ALPHA,TUMOR NECROSIS FACTOR LIGAND S ...	Mutations
P01375	TNF, TNFA, TNFSF2	ESCHERICHIA COLI	HUMAN	CACHECTIN,TNF-ALPHA,TUMOR NECROSIS FACTOR LIGAND S ...	Mutations
P01375	TNF, TNFA, TNFSF2	ESCHERICHIA COLI	HUMAN	CACHECTIN,TNF-ALPHA,TUMOR NECROSIS FACTOR LIGAND S ...	Mutations
P01375	TNF, TNFA, TNFSF2	ESCHERICHIA COLI	HUMAN	CACHECTIN,TNF-ALPHA,TUMOR NECROSIS FACTOR LIGAND S ...	Mutations
	--	--	SYNTHETIC CONSTRUCT	--
	--	--	SYNTHETIC CONSTRUCT	--

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402