FEATURES

FAMILY

DESCRIPTION

Also known as PULA_STRPN, spuA. Virulence factor (By similarity). Involved in the degradation of glycogen of the mammalian host cells (PubMed:21565699). Hydrolyzes the alpha-1, 6-branchpoints of glycogen (PubMed:20497336, PubMed:21565699). Hydrolyzes pullulan. Does not hydrolyze dextran (PubMed:20497336). Binds to mouse lung alveolar type II cells that are rich in glycogen stores. Is an alpha-glucan-specific carbohydrate-binding protein, which binds to amylose (pure alpha-(1, 4)-linked glucose), amylopectin (alpha-(1, 4)-linked glucose with alpha-(1, 6) branch points), pullulan (linear polymer of mixed alpha-(1, 4)- and alpha-(1, 6)-linked glucose) and glycogen (similar to amylopectin with more frequent alpha-(1, 6) branch points) in vitro. Does not bind to dextran (a linear polymer of alpha-(1, 6)-linked glucose) (PubMed:17187076).

EXTERNAL LINKS

spuA

Pullulanase A

spuA

Molecular Synopsis