FEATURES

FAMILY

DESCRIPTION

Also known as V5NTD_NAJAT, V5NTD. Hydrolyzes nucleotides into nucleosides (By similarity). Snake venom 5'-nucleotidases are widely distributed among venomous snake taxa, but there is a lack of information about their biological activities. They have been shown to inhibit platelet aggregation. This effect may be due to the liberation of inhibitory AMP or adenosine by its action on ADP released upon initiation of aggregation. Venom 5'-nucleotidases are also known to synergistically act in vivo with other toxins like ADPases, phospholipases, and disintegrins to exert a more pronounced anti-coagulant effect. Trimer or tetramer.

EXTERNAL LINKS

uniprot
enzyme classification

V5NTD

Snake venom 5'-nucleotidase

V5NTD

Molecular Synopsis