FEATURES

FAMILY

DESCRIPTION

Also known as L14AA_XENLA, lsm14a-a, lsm14a, rap55a-a. RNA-binding component of messenger ribonucleoprotein complexes (mRNPs), storage particles that mask maternal mRNAs from the translational apparatus during oocyte maturation (PubMed:17074753). Acts as a repressor of mRNA translation (PubMed:17074753). Probably involved in the storage of translationally inactive mRNAs in the cytoplasm in order to prevent their degradation (PubMed:17074753). Component of a ribonucleoprotein (RNP) complex, at least composed of lsm14a/rap55a, ybx2/frgy2, ddx6/Xp54 and eif4enif1/4E-T. Also forms a complex with prmt1 independently of ybx2/frgy2. Interacts with ddx6/Xp54 but does not appear to directly bind ybx2/frgy2. Different translationally-repressed mRNP complexes probably exist that contain either lsm14a/rap55a or lsm14b/rap55b depending on the developmental stage.

lsm14a-a

Structural Ligandability

Domains Chains

Distribution