FEATURES

FAMILY

Classic translation factor GTPase family

DESCRIPTION

Also known as EF2_METTP, fusA. Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.

EXTERNAL LINKS

uniprot
enzyme classification

fusA

Elongation factor 2

fusA

Molecular Synopsis