FEATURES

FAMILY

DESCRIPTION

Also known as MFPA_MYCS2, mfpA. When present on multicopy plasmids confers increased resistance to fluoroquinolone antibiotics such as ciprofloxacin and sparfloxacin but not the quinolone nalidixic acid (PubMed:11709313). Forms a structure that exhibits size, shape and electrostatic similarity to B-form DNA; it may bind to DNA gyrase which is postulated to protect it from fluoroquinolones (By similarity). Homodimer. Probably interacts with DNA gyrase.

EXTERNAL LINKS

uniprot
enzyme classification

mfpA

Pentapeptide repeat protein MfpA

mfpA

Molecular Synopsis