FEATURES

FAMILY

DESCRIPTION

Also known as RRAAH_BURM9, BMA10229_A3218. Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity). Homotrimer.

EXTERNAL LINKS

uniprot
enzyme classification

BMA10229_A3218

Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase

BMA10229_A3218

Structural Ligandability

Domains Chains

Distribution