MSX2 (Homeobox protein MSX-2)
FEATURES
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ORGANISM
Pan troglodytes
FAMILY
DESCRIPTION
Also known as MSX2_PANTR, MSX2. Acts as a transcriptional regulator in bone development. Represses the ALPL promoter activity and antagonizes the stimulatory effect of DLX5 on ALPL expression during osteoblast differentiation. Probable morphogenetic role. May play a role in limb-pattern formation. In osteoblasts, suppresses transcription driven by the osteocalcin FGF response element (OCFRE). Binds to the homeodomain-response element of the ALPL promoter (By similarity).
Also known as MSX2_PANTR, MSX2. Acts as a transcriptional regulator in bone development. Represses the ALPL promoter activity and antagonizes the stimulatory effect of DLX5 on ALPL expression during osteoblast differentiation. Probable morphogenetic role. May play a role in limb-pattern formation. In osteoblasts, suppresses transcription driven by
MSX2 logo

MSX2

Homeobox protein MSX-2

Molecular Synopsis