dphB (Diphthine synthase)
FEATURES
Loading...
Loading...
ORGANISM
Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1)
FAMILY
DESCRIPTION
Also known as DPHB_METMJ, dphB. S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis. Homodimer.
Also known as DPHB_METMJ, dphB. S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide bio
dphB logo

dphB

Diphthine synthase

Molecular Synopsis