pyrR (Bifunctional protein PyrR)
FEATURES
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ORGANISM
Hungateiclostridium thermocellum (strain ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372)
FAMILY
DESCRIPTION
Also known as PYRR_HUNT2, pyrR. Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes., Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. Homodimer and homohexamer; in equilibrium.
Also known as PYRR_HUNT2, pyrR. Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.
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pyrR

Bifunctional protein PyrR

Molecular Synopsis