secA (Protein translocase subunit SecA)

FEATURES

FAMILY

DESCRIPTION

Also known as SECA_BURM7, secA. Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.

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EXTERNAL LINKS

secA

Protein translocase subunit SecA

LIGANDABILITY MUTATIONS

secA

Molecular Synopsis