FEATURES

DESCRIPTION

Also known as GNK2_GINBI, GNK2, GNK2-1. Possesses antifungal activity against F.oxysporum, T.reesei and C.albicans. Weakly inhibits the aspartic acid protease pepsin activity (PubMed:17338634). Exerts antifungal activity against S.cerevisiae and F.culmorum through its carbohydrate-binding specificity. Acts as a lectin that stricly recognizes alpha-1, 2-linked mannose moieties and interacts with the yeast cell wall mannan polysaccharide (PubMed:25139159). Can interfere with the fungal actin remodeling resulting to the activation of an actin-dependent cell death (PubMed:26315821). Binds actin in vitro.

EXTERNAL LINKS

uniprot
enzyme classification

GNK2

Antifungal protein ginkbilobin-2

GNK2

Molecular Synopsis