FEATURES

FAMILY

DESCRIPTION

Also known as END3_AJECN, END3. Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity). Component of the PAN1 actin cytoskeleton-regulatory complex.

EXTERNAL LINKS

uniprot
enzyme classification

END3

Actin cytoskeleton-regulatory complex protein END3

END3

Structural Ligandability

Domains Chains

Distribution