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FAMILY

DESCRIPTION

Also known as LPXH_KLEP7, lpxH. Hydrolyzes the pyrophosphate bond of UDP-2, 3-diacylglucosamine to yield 2, 3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

Also known as LPXH_KLEP7, lpxH. Hydrolyzes the pyrophosphate bond of UDP-2, 3-diacylglucosamine to yield 2, 3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the ...

EXTERNAL LINKS

uniprot
enzyme classification

lpxH

UDP-2, 3-diacylglucosamine hydrolase

Mutations

Mutation(s) distribution

Mutations table

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