FEATURES

FAMILY

DESCRIPTION

Also known as PCNA_NITMS, pcn. Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.

EXTERNAL LINKS

uniprot
enzyme classification

pcn

DNA polymerase sliding clamp

Mutations

Mutation(s) distribution

Mutations table

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