pcn (DNA polymerase sliding clamp)

FEATURES

ORGANISM

Nitrosopumilus maritimus (strain SCM1)

FAMILY

DESCRIPTION

Also known as PCNA_NITMS, pcn. Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.

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EXTERNAL LINKS

UNIPROT
ENZYME CLASSIFICATION

pcn

DNA polymerase sliding clamp

MOLECULAR SYNOPSIS STRUCTURAL LIGANDABILITY

pcn

Molecular Synopsis