FEATURES

DESCRIPTION

Also known as BIODA_ARATH, BIO3-BIO1, BIO1, BIO3. Bifunctional enzyme that catalyzes two different reactions involved in the biotin biosynthesis., Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7, 8-diaminopelargonic acid (DAPA) to form an ureido ring., Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7, 8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor. Homodimer.

Also known as BIODA_ARATH, BIO3-BIO1, BIO1, BIO3. Bifunctional enzyme that catalyzes two different reactions involved in the biotin biosynthesis., Catalyzes a mechanistically unusual reaction, th ...

EXTERNAL LINKS

uniprot
enzyme classification

BIO3-BIO1

Bifunctional dethiobiotin synthetase/7, 8-diamino-pelargonic acid aminotransferase, mitochondrial

Mutations

Mutation(s) distribution

Mutations table

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