FEATURES

FAMILY

DESCRIPTION

Also known as SYG1_CAEEL, syg-1. Cell adhesion protein (PubMed:15035988). Involved in synapse formation in the HSNL egg-laying motor neuron (PubMed:12628183, PubMed:15035988, PubMed:21858180, PubMed:24485456). Inhibits assembly of the SCF(sel-10) E3 ubiquitin ligase complex at synapses, and protects them from elimination (PubMed:17626846). Also required for F-actin assembly at the synaptic region and for axon branch formation (PubMed:24439377). Interacts with skr-1 (PubMed:17626846). Interacts with syg-2 (PubMed:21858180, PubMed:24485456). Interacts with the WAVE regulatory complex; the interaction leads to formation of a synaptic F-actin network that is required for synapse formation and axon branching (PubMed:24439377).

EXTERNAL LINKS

syg-1

Mutations

Mutation(s) distribution

Mutations table