FEATURES

FAMILY

DESCRIPTION

Also known as CHI2_YERET, chi2. Part of an orally active toxin complex (TC) with strong insecticidal effects on larvae of the Coleoptera Costelytra zealandica, Acrossidius tasmania and Adoryphorus couloni and some Lepidoptera larvae (PubMed:21278295). The TC has an endochitinase activity (PubMed:21278295, PubMed:22158901) (Probable). This subunit might aid infection by degradation of the larval peritrophic membrane (Probable). Semipurified toxin complex consists of at least YenA1-YenA2-YenB-YenC1-YenC2-Chi1-Chi2 (PubMed:21278295). The Yen-TC:K9 subcomplex is about 26 nm tall and 22 nm in diameter with 5-fold symmetry and 5 copies of YenA1, YenA2, Chi1 and Chi2; the chitinase subunits may be solvent accessible on the exterior the complex (PubMed:22158901). The Yen-TC:K9 subcomplex has no insecticidal activity (PubMed:22158901). The native complex with additional YenB, YenC1 and YenC2 subunits is 16 nm taller and is insecticidal; the toxicity-conferring subunits are present at about 1 copy each (PubMed:22158901).

EXTERNAL LINKS

chi2

Chitinase 2

chi2

Molecular Synopsis