FEATURES

FAMILY

DESCRIPTION

Also known as SULA_ECO55, sulA. Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. Interacts with FtsZ.

EXTERNAL LINKS

uniprot
enzyme classification

sulA

Cell division inhibitor SulA

sulA

Structural Ligandability

Domains Chains

Distribution