sulA (Cell division inhibitor SulA)
FEATURES
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ORGANISM
Escherichia coli (strain 55989 / EAEC)
FAMILY
DESCRIPTION
Also known as SULA_ECO55, sulA. Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. Interacts with FtsZ.
Also known as SULA_ECO55, sulA. Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore prevent
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sulA

Cell division inhibitor SulA

Molecular Synopsis