iscA (Iron-binding protein IscA)
FEATURES
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ORGANISM
Escherichia coli O45:K1 (strain S88 / ExPEC)
FAMILY
DESCRIPTION
Also known as ISCA_ECO45, iscA. Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB. Homodimer; may form tetramers and higher multimers.
Also known as ISCA_ECO45, iscA. Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cyste
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iscA

Iron-binding protein IscA

Molecular Synopsis