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FEATURES

FAMILY

class V-like SAM-binding methyltransferase superfamily

DESCRIPTION

Also known as ATXR5_RICCO, ATXR5. Histone methyltransferase that specifically monomethylates 'Lys-27' of histone H3 (H3K27me1). Has much higher activity on nucleosomes containing H3.1 than H3.3. Involved in the formation of constitutive heterochromatin and the silencing of heterochromatic elements. Homodimer.

Also known as ATXR5_RICCO, ATXR5. Histone methyltransferase that specifically monomethylates 'Lys-27' of histone H3 (H3K27me1). Has much higher activity on nucleosomes containing H3.1 than H3.3. Invo ...

EXTERNAL LINKS

uniprot
enzyme classification

ATXR5

Probable Histone-lysine N-methyltransferase ATXR5

Mutations

Mutation(s) distribution

Mutations table

Search Mutation

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