FEATURES

FAMILY

DESCRIPTION

Also known as LYT1_LYCER, LYT1. Has antimicrobial activity against Gram-positive bacterium S.aureus (MIC=3.79 uM), Gram-negative bacterium E.coli (MIC=7.81 uM) and yeasts C.krusei (MIC=26.3 uM) and C.neoformans (MIC=13.2 uM). Has hemolytic activity against rabbit erythrocytes. Forms pores in lipid bilayers in vitro; pore formation is reduced when cholesterol is present in the bilayers.

EXTERNAL LINKS

uniprot
enzyme classification

LYT1

Mutations

Mutation(s) distribution

Mutations table