FEATURES

DESCRIPTION

Also known as PHNZ_UNCHF, phnZ. Involved in the degradation of the organophosphonate 2-aminoethylphosphonic acid (2-AEP) (Probable). Catalyzes the cleavage of the carbon-phosphorus bond of (2-amino-1-hydroxyethyl)phosphonic acid to yield glycine and phosphate through an oxidative mechanism (PubMed:22564006, PubMed:24198335, PubMed:24706911). It reacts stereospecifically with the R-enantiomer of (2-amino-1-hydroxyethyl)phosphonic acid and is also able to use (R, R)-2-amino-1-hydroxypropylphosphonate as substrate (PubMed:24706911). Monomer.

EXTERNAL LINKS

uniprot
enzyme classification

phnZ

2-amino-1-hydroxyethylphosphonate dioxygenase (glycine-forming)

phnZ

Molecular Synopsis