FEATURES

FAMILY

DESCRIPTION

Also known as HMP1_GIAIA, hmpA-1, FLHb-1. Flavohemoprotein involved in nitric oxide (NO) detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the protozoan parasite from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress. May also be involved in O(2) detoxification (By similarity). Monomer.

EXTERNAL LINKS

uniprot
enzyme classification

hmpA-1

Flavohemoprotein-1

hmpA-1

Structural Ligandability

Domains Chains

Distribution