FEATURES

FAMILY

DESCRIPTION

Also known as HMFO_METS6, MPQ_0130. Involved in the degradation and detoxification of 5-(hydroxymethyl)furfural (HMF) by mediating its oxidation to furan-2, 5-dicarboxylate (FDCA), a biobased platform chemical for the production of polymers. Active with a wide range of aromatic and aliphatic primary alcohols and aldehydes: acts on alcohol groups and requires the spontaneous hydration of aldehyde groups for their oxidation (PubMed:24271187, PubMed:24802551). To a lesser extent, is also able to catalyze the oxidation of thiols that are structurally similar to its alcohol substrates, yielding the corresponding thiocarbonyls (PubMed:25284255). Monomer.

EXTERNAL LINKS

uniprot
enzyme classification

MPQ_0130

5-(hydroxymethyl)furfural oxidase

MPQ_0130

Molecular Synopsis