FEATURES

FAMILY

NAD(P)-dependent epimerase/dehydratase family

DESCRIPTION

Also known as GALE_BIFL2, lnpD. Involved in the metabolism of galactose. Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD. Can also epimerize UDP-GalNAc to UDP-GlcNAc. Involved in the lacto-N-biose I/galacto-N-biose (LNB/GNB) degradation pathway, which is important for host intestinal colonization by bifidobacteria. Homodimer.

EXTERNAL LINKS

uniprot
enzyme classification

lnpD

UDP-glucose 4-epimerase

lnpD

Molecular Synopsis