FEATURES

FAMILY

metallo-dependent hydrolases superfamily

DESCRIPTION

Also known as LIGJ_SPHSK, ligJ. Contributes to the degradation of lignin at the level of the protocatechuate 4, 5-cleavage pathway. Catalyzes the hydration of the double bond of (3Z)-2-keto-4-carboxy-3-hexenedioate (KCH) to (4S)-4-carboxy-4-hydroxy-2-oxoadipate (CHA, also named (2S)-2-hydroxy-4-oxobutane-1, 2, 4-tricarboxylate) (PubMed:29658701, PubMed:30207699). Is involved in the catabolism of both vanillate and syringate (PubMed:11092855). Homodimer.

EXTERNAL LINKS

uniprot
enzyme classification

ligJ

2-keto-4-carboxy-3-hexenedioate hydratase

Mutations

Mutation(s) distribution

Mutations table

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