FEATURES

FAMILY

DESCRIPTION

Also known as LCTB_ACEWD, lctB, etfB. The lactate dehydrogenase-Etf complex catalyzes the oxidation of lactate to pyruvate. It uses flavin-based electron confurcation to drive endergonic lactate oxidation with NAD(+) as oxidant at the expense of simultaneous exergonic electron flow from reduced ferredoxin to NAD(+). The electron transfer flavoprotein (Etf) mediates the electron transfer between the different donors and acceptors. Part of the stable heterotrimeric lactate dehydrogenase-Etf complex, which is formed by the lactate dehydrogenase LctD and the electron-transferring flavoprotein (Etf) alpha (LctC) and beta (LctB) subunits.

EXTERNAL LINKS

lctB

Lactate dehydrogenase (NAD(+), ferredoxin) subunit LctB

Mutations

Mutation(s) distribution

Mutations table

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